Endocrine Abstracts

Introduction: Acromegaly is a chronic disease that affects morphology and organ functions. These changes lead to clinically relevant comorbidities. Untreated acromegaly reduces life expectancy by 10 years, mostly due to cardiovascular events, malignancies and respiratory disorders. We present the results of a series of 109 acromegalic patients at a single institution.Methods: Lung function tests were performed under standardized conditions in patients wi...

The prevalence of growth hormone deficiency (GHD) following traumatic brain injury (TBI) based on IGF-1 testing differs in literature between 10 and 40%. In our cohort the frequency of IGF-1 values <1 S.D. was 25%. If our patients had a minimal hepatocellular damage, the IGF-1 value could be <1 S.D. We evaluated the effects of BMI and liver function on IGF-1 and IGFBP-3 values in patients following TBI or subarachnoidal haemorrhage (SAH).<...